CVS Health CEO Larry Merlo said the company's merger with Aetna will create a data-driven health care model that is easier for people to use, less expensive and patient-centered. Merlo said the combined company will prioritize localizing, simplifying and improving health care.
The Biden Cancer Initiative summit last week resulted in 57 commitments and recommitments by companies and organizations building from the White House Cancer Moonshot as part of an effort to reduce the burdens on cancer patients and families. The Bristol-Myers Squibb Foundation, which already had promised $25 million in grants to reduce health disparities, said it would continue funding support, and Deloitte said it will hold a competition in 2019 for early cancer detection tests.
Patients with type 2 diabetes whose intra-individual standard deviation of A1C levels was below the median had a lower all-cause mortality risk than those whose A1C-SD was above the median, regardless of whether an individual's average A1C level was above or below the median, according to a study in Diabetes, Obesity and Metabolism. Italian researchers used a cohort of 8,290 patients and noted that A1C variability "is a strong, independent predictor of all-cause mortality in type 2 diabetes and appears to be even more powerful than average A1C in predicting mortality."
Researchers analyzed 422 patients with prediabetes from the STOP DIABETES study and found that none of the high-risk patients who received a GLP-1 receptor agonist, low-dose metformin and pioglitazone progressed to type 2 diabetes, compared with 5% of intermediate-risk participants who received metformin and pioglitazone, and 11% of high- and intermediate-risk patients who received lifestyle therapy only. The findings were published in The Lancet Diabetes & Endocrinology.
An analysis of sleeping patterns for almost 2,000 adults found those who had irregular bedtimes had higher BMI readings, blood glucose levels, blood pressure and A1C, compared with those who had more regular sleeping patterns, according to a study published in Scientific Reports. People with irregular sleep patterns also had a higher risk of heart attack, stroke, depression and stress.
A study in JAMA Network Open showed that both body mass index and weight for length measures similarly predicted that children younger than age 2 who were overweight had increased odds of adverse cardiometabolic risk markers -- such as increased BMI z-scores, fat mass index, subscapular and triceps skinfolds, and waist circumference -- in early adolescence, compared with those who weren't overweight. However, the findings showed within-subject BMI measurements were associated with increased consistency over time, indicating that BMI may be more stable than WFL.
Chinese researchers found that men who had increased levels of total physical activity and moderate to vigorous physical activity were less likely to develop Parkinson's disease, with every 10 metabolic equivalent of task-hours per week increase in total or moderate to vigorous physical activity tied to a 10% and 17% drop in Parkinson's risk, respectively. The findings in JAMA Network Open "may help guide physicians and health care policymakers in making recommendations and developing guidelines with respect to the degree of physical activity that can help reduce the risk of [Parkinson's disease] at both the individual level and the population level," researchers wrote.
A survey of more than 5,000 corporate board members from around the world found innovation, overall, is not a top strategic challenge for the majority of them, according to a report in Harvard Business Review. Health care and IT directors were most likely to view innovation as a top strategic challenge, and these companies also had higher-rated processes for innovation.
The Illinois Supreme Court ruled in Oswald v. Beard that a state tax exemption law, which includes guidelines for creating nonprofit hospital tax exemptions, is constitutional. Illinois Health and Hospital Association General Counsel Mark Deaton said the state's model potentially could be used by other states.
Researchers at the University of California at San Francisco found that gallium-68 PSMA-11 PET/MRI yielded region-specific sensitivities of 74% and 73% in localizing prostate tumors using the alternative neighboring approach and population-averaged generalized estimating equation, respectively, compared with sensitivities of 50% and 69% with multiparametric MRI. The findings in a radiology journal, based on scans from 32 men with prostate cancer, also showed similar region-specific specificities between the modalities.
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