Lab Sciences
Top stories summarized by our editors
9/22/2017

A study in the journal The Lancet found one-quarter of those who donated blood frequently for two years developed iron deficiency. However, the UK study involving more than 45,000 blood donors also found that donating blood every eight weeks for men and every 12 weeks for women was not associated with risk of major adverse effects.

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HealthDay News
9/22/2017

Guidelines developed by scientists from the University of Texas MD Anderson Cancer Center in Houston focus on monitoring and treating potentially fatal toxicities experienced by patients receiving chimeric antigen receptor T-cell therapies. The guidelines in the journal Nature Reviews Clinical Oncology recommend monitoring, grading and treating toxicities such as cytokine-release syndrome and CAR T-cell-related encephalopathy syndrome.

9/22/2017

A $2.5 million contract for a two-year project was awarded by the FDA to ChromaTan for the development of a continuous purification platform for monoclonal antibody production.

9/22/2017

The FDA has granted emergency-use authorization for the Advia Centaur Zika test developed by Siemens Healthcare Diagnostics. The designation covers use in certified laboratories.

9/20/2017

A World Health Organization report said the drug-development pipeline contains too few antibiotics to replace those that become resistant to pathogens. The WHO said there are 51 antibiotics and 11 biological agents for bacterial pathogens, such as Clostridium difficile, but noted most new drugs under development for gram-negative bacteria are modifications of existing antibiotics.

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World Health Organization
9/20/2017

Ontario girl Aunika Kerr will celebrate her first birthday this week after undergoing a thymus tissue transplant July 7 at Duke University Hospital. Kerr was born without a functioning thymus gland, rendering her vulnerable to even the most minor infections such as a cold.

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Simcoe (Ontario)
9/20/2017

The National Organ and Tissue Transplant Organization in India has received 5,000 pledges for organ donation, raising public awareness about organ donation and the need for hospitals to install equipment and protocols to facilitate transplants.

9/20/2017

The European Medicines Agency says it found no conclusive evidence of any difference in risk of inhibitor development between treatment with recombinant or plasma-derived factor VIII medicines. The report follows a 2016 study that suggested risk might be higher in patients treated with recombinant factor VIII.

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Regulatory Focus
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European Medicines Agency
9/20/2017

A study in the Journal of Thrombosis and Haemostasis showed that it was safe and effective to treat patients who had undergone liver surgery with an extended pharmacologic thromboprophylaxis regimen to prevent venous thromboembolism. The 124-patient study found no deep vein thrombosis or pulmonary embolic events documented in 90 days after hepatic resection for cancer. In addition, transfusion rates were 10.5% or less for the intraoperative and postoperative periods and overall at 5.6%, 8.1% and 10.5%, respectively.

9/20/2017

Investigators from the UK's University of Southampton discovered a natural killer cell receptor that is capable of recognizing numerous viruses, which could lead to the development of a new vaccine to treat dengue, Zika and hepatitis C. Findings were published in the journal Science Immunology.

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Deccan Herald (India)