Lab Sciences
Top stories summarized by our editors
5/18/2018

In a study of people with HIV, more frequent use of methamphetamine was found to be associated with changes in gene expression and a 50% increased risk of disease progression, according to a study in the journal Brain, Behavior, and Immunity. The findings were based on an analysis of gene expression in 55 people.

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methamphetamine
5/18/2018

Two French gene therapy companies, Vectalys and FlashCell, are merging under the name Flash Therapeutics. Discovery and development of therapies for blood and liver diseases will continue.

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Endpoints News
5/17/2018

The first experimental Ebola vaccines from the World Health Organization have arrived in the Democratic Republic of Congo, and the country will begin inoculations this weekend. Meanwhile, Public Health Minister Oly Ilunga Kalenga said an Ebola case had been found in Mbandaka, a city of about 1 million.

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Reuters, Reuters
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Ebola, World Health Organization
5/17/2018

The Cherokee Nation began a hepatitis C prevention program three years ago with the goal of screening 80,000 of its 350,000 members, and over 50% of the target group has been screened, while 90% of people with detected cases who have received care have responded to treatment. John Ward of the CDC said the program is "a trailblazing project for the entire country."

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ABC News
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Cherokee Nation, John Ward, CDC
5/17/2018

Roche will present data from its late-stage HAVEN 3 and HAVEN 4 clinical trials evaluating its candidate Hemlibra, or emicizumab, on May 21 at the World Federation of Hemophilia 2018 World Congress in Scotland. The data include positive results showing the efficacy of Hemlibra in hemophilia A patients without factor VIII inhibitors dosed once weekly or every other week in the HAVEN 3 study and of doses given every four weeks for hemophilia A patients with or without factor VIII inhibitors in the HAVEN 4 trial.

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PharmaBiz (India)
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Roche
5/17/2018

The World Health Organization has released a list of 113 essential diagnostic tests for common illnesses and global priority diseases. The list includes assays for malaria, hepatitis B and C, and HIV.

5/17/2018

The FDA has given final approval for Eagle Pharmaceuticals' ready-to-dilute bendamustine hydrochloride solution in a 500ml admixture, an injection that requires no reconstitution, to treat patients with chronic lymphocytic leukemia and indolent B-cell non-Hodgkin lymphoma.

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Reuters, Seeking Alpha
5/16/2018

Dosing has begun in a Phase I/II clinical trial of BioMarin Pharmaceutical's gene therapy candidate valoctocogene roxaparvovec for patients with severe hemophilia A with pre-existing adeno-associated virus type 5 antibodies. The trial is expected to run through June 2024.

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Seeking Alpha
5/15/2018

A study of 1,959 young, nulliparous, nonpregnant women in Burkina Faso, where malaria is hyperendemic, found that weekly administration of iron supplements was not associated with improved iron status, decreased anemia or increased risk of malaria, and researchers suggested re-evaluating World Health Organization guidance on supplementation. The findings were published in the Journal of Infectious Diseases.

5/15/2018

LogicBio Therapeutics will present information on its gene editing technology for hemophilia B and methylmalonic acidemia at the American Society of Gene & Cell Therapy annual meeting. The company will discuss data from a study that tested a single injection in mouse models of hemophilia B.

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Rare Disease Report