A 25-year-old woman received a transplant of ovarian tissue frozen more than 10 years ago at New York University Winthrop Hospital. "You don't want to freeze the whole ovary. The immature eggs are on the surface, so we peel off that layer. This is what we cut into tiny slivers," said Dr. Kutluk Oktay.
A study by Canadian researchers compared five commercially available serologic assays based on specificity and sensitivity and found the tests generally provided reproducible results, and sensitivity could be increased by testing a second sample taken a few weeks after the initial sample. The findings were published in the journal Emerging Infectious Diseases.
Drinking water laced with the malaria drug chloroquine reduced viral load in pregnant mice infected with the Zika virus and their offspring, according to a study published in Scientific Reports. The drug is inexpensive, readily available and safe, and should be tested in human trials, study co-author Alexey Terskikh said.
A grant from Innovate UK worth over $798,000 will support Genedrive, National Health Service Tayside and the University of Dundee in their work to develop a centrifuge-free, disposable plasma separation device for use with Genedrive's hepatitis C virus assay.
Chinese manufacturer Motic developed the EasyScan GO, a microscope that uses artificial intelligence and software to quantify malaria parasites in blood samples. The device is also intended to identify the strain of malaria present.
A team led by scientists from the University of Pennsylvania's Perelman School of Medicine found evidence of a new species, Plasmodium lomamiensis, a relative of the human malaria parasite Plasmodium falciparum, in wild bonobos. Plasmodium was not found in most of the bonobo populations tested, and the study team could not determine the reason for the absence.
Concentrations of five microRNAs in saliva yielded 85% accuracy in identifying youths whose concussion symptoms persisted one month after injury, compared with about 65% accuracy using the Standardized Concussion Assessment Tool 3, researchers reported in the journal JAMA Pediatrics. The findings were based on data involving 52 children with concussions ages 7 to 21.
In a study in the journal Hepatology, researchers from University of Texas Health found that treatment with the drugs glecaprevir and pibrentasvir resulted in high rates of sustained virologic response in hepatitis C patients with genotypes 1 and 4 who did not respond to other direct-acting antivirals.
A joint team of investigators is studying how and where a malaria vaccine can be stabilized to create a stronger vaccine. The research seeks to gain an improved understanding of how the human immune system identifies malaria parasites using the RTS,S vaccine.
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