In nine countries in sub-Saharan Africa, almost 1 in 4 blood donors from 2000 to 2017 tested positive for Plasmodium parasites, according to a review of data from 26 studies. The rate varied by country from zero to 74%.
British researchers analyzed odors from the used socks of children with and without malaria in western Kenya to determine what compounds might be attractive to Anopheles mosquitoes. The study in the journal Proceedings of the National Academy of Sciences found greater amounts of the aldehydes heptanal, octanal and nonanal in children with malaria.
Diagnostics manufacturer Genetic Signatures, based in Australia, announced that its polymerase chain reaction-based detection kit that can identify carbapenemase-producing organisms and extended spectrum beta-lactamase has been granted the CE mark. The EasyScreen ESBL & CPO Kit can detect 16 beta-lactam and carbapenem-resistant pathogen targets in less than three hours.
The World Health Organization has issued a recommendation that anyone receiving the dengue vaccine should first undergo diagnostic testing to determine if they have been exposed to the disease. The new guideline was issued in light of controversies regarding the effect of Sanofi Pasteur's dengue vaccine Dengvaxia on children younger than 9 years who were vaccinated in the Philippines.
Italian investigators found that adding ribavirin to direct-acting antiviral therapies to treat hepatitis C virus infections with mixed cryoglobulinemia increased immunological response and reduced serum cryocrit among patients achieving sustained virologic response at 12 weeks. The research was published in the journal Archives of Virology.
A paper in the journal The Annals of Thoracic Surgery describes how Daxor's BVA-100 blood volume analyzer is capable of illuminating intravascular fluid derangements missed by standard tests and has 98% accuracy in quantifying whole blood and red blood cell volume.
Researchers analyzed data for 2,951 orthopedic surgery patients and found that median hospital stays and 30-day readmission rates fell after introduction of a comprehensive patient blood management program. Blood transfusion use dropped, and trigger hemoglobin levels decreased from 7.8±1.0 to 6.9±1.1 g/dL.
The Malaria Summit London, co-hosted by the UK, Rwanda and Swaziland, has resulted in almost $4 billion in new pledges to support malaria prevention and research. At the 7th Multilateral Initiative on Malaria Pan African Malaria Conference in Senegal, researchers warned that famine and conflict threaten the past decade's progress against malaria.
A woman in her 60s and a man in his 80s with severe neovascular age-related macular degeneration experienced improved sight after receiving implants of stem cell-derived retinal pigment epithelium cells. "This study represents real progress in regenerative medicine and opens the door to new treatment options for people with age-related macular degeneration," said researcher Pete Coffey of University College London.
At a Donate Life Month celebration, Sue Landacre, a registered nurse and clinical coordinator at United Hospital Center in Bridgeport, W.Va., shared the story of the death of her 13-year-old son Jake 12 years ago and her decision to donate his eyes and tissue. "It's a rewarding thing. It's the last gift they can give and the last gift you can give for them," Landacre said.
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