A team of researchers from the Netherlands developed a liquid biopsy called thromboSeq that identified tumor RNA in thrombocytes with nearly 90% accuracy in diagnosing non-small-cell lung cancer, according to a study in the journal Cancer Cell.
The FDA approved VBI Vaccines' investigational new drug application for its immunotherapy candidate VBI-1901, which is being developed as a treatment for patients with glioblastoma multiforme. A Phase I/IIa study of the drug is expected to be launched later this year.
North West London Pathology signed a $252 million managed equipment services contract with Abbott for the supply of North West London's Alinity h hematology diagnostics instruments, Alinity ci clinical chemistry and immunoassay and AlinIQ professional services and informatics solution. Abbott said the deal will help North West London in maximizing productivity, delivering key information for clinical decision-making and speeding up test results delivery.
Tim Anegon, who died from complications after a liver transplant, was an eye tissue donor, and his gift aided researchers studying diabetic eye disease, the leading cause of vision impairment among adults of working age. "A lot of the research being done on animal and cell models still teaches a lot, but we're missing that link in translating to the human pathology," Dr. Patrice Fort told Anegon's family during a meeting at the University of Michigan's Kellogg Eye Center.
Researchers found that the Ebola virus has the potential to replicate and spread through human retinal pigment epithelial cells, according to a study in the journal Translational Vision Science & Technology. "We speculate that infected cells activate the type 1 IFN response, which would limit spread of infection, but that these cells also restrict innate and adaptive immune responses, which otherwise would clear the virus from the eye," the study authors wrote.
Microsoft co-founder Bill Gates donated a record-breaking $4.6 billion to the Bill & Melinda Gates Foundation Monday and on Tuesday announced the launch of an anti-malaria campaign. Gates asked his blog followers to read a malaria-related post and then take a related quiz, promising to donate one mosquito bed net per participant to families in Mozambique.
Plastic surgeon Jesse Selber, who specializes in cancer reconstruction, was part of a multi-disciplinary surgery at MD Anderson Cancer Center in which tissue from a patient's twin sister was used to cover the site where a rare tumor was removed. Selber said it was one of the largest tissue transplantations on record, and while family members are not always well-matched, the twin sisters were 100% genetically compatible and identical.
H3 Biomedicine's orally administered lead candidate, H3B-8800, was granted orphan drug designation by the FDA as a treatment for patients with acute myeloid leukemia and chronic myelomonocytic leukemia. The drug is in ongoing early-stage clinical trials to evaluate its safety and efficacy.
A deal to sell 2.5 million ordinary shares was reached by diagnostic company Oxford Immunotec with investment bank BTIG. Net proceeds from the agreement, under which the company granted an option for the bank to buy up to 375,000 additional shares, will be used as working capital, as well as to support general corporate functions.
Researchers identified 35 adults with Zika virus infections who were treated in Brazil for neuroinflammatory conditions, according to a study in the journal JAMA Neurology. The most common condition was Guillain-Barre syndrome, while encephalitis, transverse myelitis and chronic inflammatory demyelinating polyneuropathy were also reported.