Otsuka Pharmaceutical Senior Director of Applied Innovation Pravin Jadhav said the company manages any overload of new ideas driven by digital integration by avoiding the "shiny-object syndrome" in drug development and tying innovation to the concepts of idea, action and value. Jadhav said the pharmaceutical industry can create value through digital integration, which could lead to improved clinical trial execution and therapeutic improvements.
Researchers found that adults born preterm who were exclusively breastfed had less profound smaller heart chambers between ages 23 to 28, compared with those who were given an exclusive formula-based diet, indicating the protective effect of breast milk against heart diseases. The findings were published in Pediatric Research.
The CMS indicated officials are inclined to allow Medicare Part D subscribers to change their drug plan after open enrollment closes if they chose a plan that doesn't suit their needs due to changes in the Medicare Plan Finder tool.
About one in five people are highly sensitive, meaning they feel and think more deeply, experience more work stress, are easily affected by criticism and are more prone to burnout. To reduce overstimulation, highly sensitive managers should consider holding office hours to handle issues instead of having an open door policy, suggests career coach Melody Wilding.
Senate Democrats have floated the idea of repealing the Affordable Care Act's so-called Cadillac tax as part of efforts to negotiate a government funding agreement by a Dec. 20 deadline, according to a congressional aide with knowledge of the talks. The tax on generous health plans is set to take effect in 2022.
An analysis of drug spending at 26 hospitals from four US health systems found spending on costly new immunotherapies for small cell lung cancer rose by 199% in the first three-quarters of this year compared with the same period a year ago. Hospital spending on medications for migraine prevention and neutropenia increased by 90% and 79%, respectively, according to the study.
CDC officials say the rate of outpatient visits involving flu-like illnesses has reached or exceeded the national baseline for a month, and high activity was observed in 12 states during the week ending Nov. 30, indicating the fastest start of flu season since 2003-04. The 2019-20 flu season also has a 40% likelihood of reaching its peak this month, and six pediatric deaths have been documented so far, according to the CDC.
The FDA is investigating the diabetes drug metformin for the presence of nitrosamines, genotoxic substances that might increase risk of cancer over time, and whether these drugs exceed the acceptable daily limit of 96 ng. FDA Center for Drug Evaluation and Research Director Dr. Janet Woodcock said recalls will be initiated if unsafe levels of nitrosamines are found.
Amgen's Avsola, or infliximab-axxq, gained the FDA's approval as the fourth biosimilar for Janssen's Remicade, or infliximab, to be combined with methotrexate to treat rheumatoid arthritis. The biosimilar is also indicated as a treatment for patients with ankylosing spondylitis, Crohn's disease, plaque psoriasis, psoriatic arthritis and ulcerative colitis.
In an effort to gain support, Senate Finance Committee Chairman Chuck Grassley, R-Iowa, and Sen. Ron Wyden, D-Ore., added provisions to their drug pricing legislation, including measures that would allow seniors to spread out their Medicare Part D out-of-pocket costs over time and lower costs for beneficiaries who exceed their deductible but do not hit Part D's catastrophic phase. The senators said they also plan to use savings from the legislation to fund health care extenders and halt funding cuts to Medicaid Disproportionate Share Hospital payments for two years.