A study found bone defects in mouse models of hemophilia A and B at birth and after an injury, but not in mice with Von Willebrand disease. Researchers said the findings in the journal Scientific Reports suggest the need for further study.
Dr. Jordan Feld of the University of Toronto and Dr. Anna Suk-Fong Lok of the University of Michigan discuss the US Preventive Services Task Force's draft recommendation of hepatitis C virus screening for pregnant women younger than 18, in addition to all adults through age 79, including pregnant women. "Testing pregnant women for HCV is good public health policy," they write.
The National Institute of Bioprocessing Research and Training of Ireland and GE Healthcare will collaborate to create training programs dealing with biopharmaceutical and cell therapy development. "What we're seeing is very strong interest in new complex types of therapeutics," said Killian O'Driscoll, director of projects at the institute.
The climate crisis could triple the transmission rates of viruses such as Ebola that can be spread from animals to humans by the year 2070, according to a study in the journal Nature Communications.
The FDA has granted 510(k) clearance to Beckman Coulter's DxA 5000 total laboratory automation system. The system can detect patient tube parameters in three seconds, helping to prevent preanalytical errors, and reduces the number of manual sample processing steps from 32 to four.
The Multiple Myeloma Research Foundation has launched its online Direct-to-Patient Registry, which will allow patients with multiple myeloma to submit their health data securely to the foundation's data repository, the MMRF CureCloud. The repository will include information from other foundation-led studies.
Clinical laboratories dealing with persistent workforce shortage should consider using the military concept of force multipliers to reduce productivity constraints and maximize limited resources, write Shawn Silver, a pathology resident at Case Western Reserve University, and Jaime Noguez, director of clinical chemistry and toxicology at University Hospitals Cleveland Medical Center. Silver and Noguez describe how the use of robotic force multipliers and automation in their laboratory significantly reduced the amount of hands-on time required by staff.
Scientists at the University of Pittsburgh have developed a device that uses red light to remove carbon monoxide from the blood and oxygenate it in tests involving rats, according to a study in the journal Science Translational Medicine. The device pumps blood from a vein in the leg through a porous membrane where it is exposed to red light.
The World Health Organization said the work to respond to Ebola virus infections in Lwemba, Democratic Republic of Congo, has resumed on a restricted basis after security issues had stalled the efforts. WHO also reported a decline in the number of new cases.
China's medical product regulatory agency has granted IASO Biotherapeutics and Innovent Biologics clearance to launch their Phase Ib/II trial in China to assess the chimeric antigen receptor T-cell therapy candidate CT103A as a treatment for patients with relapsed or refractory multiple myeloma. The agency also granted the therapy Investigational New Drug status.
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